EnvThes
DNA polymorphism
deprecated concept
MS Academic Keywords
[A. V. Khrunin] DNA polymorphism is an important factor in the interindividual variations in the reactions of patients to the same drugs. In the current study, the polymorphism in the OCT2, GGT1, HO1, and DNASE1 genes were evaluated for the correlation with cisplatin nephrotoxicity in ovarian cancer patients... , " DNA polymorphism can be defined as an inheritable genetic variant on a particular place (locus) in the genome, with a population frequency above 1% in the population. Such polymorphism can consist of one single base substitution (so called single nucleotide polymorphism or SNP), of deletions or insertions of one or several bases, or of a variable length of one repetitive DNA sequence (so called &#34 , "[Ying-Jia Shen] DNA polymorphism is the basis to develop molecular markers that are widely used in genetic mapping today. A genome-wide rice (Oryza sativa) DNA polymorphism database has been constructed in this work using the genomes of Nipponbare, a cultivar of japonica, and 93-11, a cultivar of indica. This database contains 1,703,176 single nucleotide polymorphisms (SNPs) and 479,406 Insertion/Deletions (InDels), approximately one SNP every 268 bp and one InDel every 953 bp in rice genome. Both SNPs and InDels in the database were experimentally validated...