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Preferred term

DNA fragmentation

Definition

[Qing-Li Liu] DNA fragmentation is a hallmark of cells undergoing apoptosis and is mediated mainly by thecaspase-activated DNase (CAD or DNA-fragmentation factor 40 (DFF40)), which is activated when released from its inhibitor protein (ICAD or DFF45) upon apoptosis signals.

Broader concept

biological process

Scope note

MS Academic Keywords

Creator

https://orcid.org/0000-0003-2195-3997

URI

http://vocabs.lter-europe.net/EnvThes/20983

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Created 8/3/16, last modified 2/17/19

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